PRESENTATION NO 007 : AMLOSAR
AMLOSAR
Amlodipine 10mg and Valsartan 160mg Tablets.
INTRODUCTION
Less peripheral edema than amlodipine 10 mg alone for similar BP reduction.
Well tolerated antihypertensive treatment.
Efficacy and safety.
WHAT IS AMLODIPINE-VALSARTAN?
Amlodipine/valsartan is a prescription drug.
It comes as a tablet that you take by mouth once each day.
Amlodipine/valsartan is a combination of two drugs in a single form.
It’s important to know about all the drugs in the combination because each drug may affect you in a different way.
THEURAPHATIC INDICATION
This product is used to treat high blood pressure.
Lowering high blood pressure helps prevent;
This product contains 2 medications: amlodipine and
They both work by relaxing blood vessels so blood can flow more easily.
Amlodipine is a calcium channel blocker and valsartan is an angiotensin receptor blocker (ARB).
Amlodipine/valsartan is used to treat high blood pressure.
HOW IT WORKS
Amlodipine belongs to a class of drugs called calcium channel blockers.
Valsartan belongs to a class of drugs called angiotensin II receptor blockers.
A class of drugs is a group of medications that work in a similar way.
These drugs are often used to treat similar conditions.
Amlodipine and valsartan work in different ways to relax your blood vessels, which helps to lower your blood pressure.
Amlodipine works by relaxing the muscles that tighten and narrow blood vessels.
Valsartan works by blocking the action of angiotensin II, a chemical in your body that causes blood vessels to tighten and narrow.
This helps to relax and widen your blood vessels.
MORE COMMON SIDE EFFECTS
The more common side effects that can occur with use of amlodipine/valsartan include:
If these effects are mild, they may go away within a few days or a couple of weeks.
If they’re more severe or don’t go away, talk to your doctor or pharmacist.
SERIOUS SIDE EFFECTS
Low blood pressure. Symptoms can include:
dizziness or feeling faint
chest pain
Kidney problems. Symptoms can include:
swelling of your hands, ankles, or feet
unexplained weight gain
Heart attack. Symptoms can include:
chest pain or tightness
shortness of breath
rapid heartbeat
discomfort in your upper body
PRECAUTIONS
Before taking this product, tell your doctor or pharmacist if you are allergic to either amlodipine or
This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Talk to your pharmacist for more details.
This product may increase your potassium levels.
Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist
AMLODIPINE-VALSARTAN MAY INTERACT WITH OTHER MEDICATIONS
Cholesterol drug
Simvastatin is used to help manage cholesterol levels.
Taking this drug with amlodipine, one of the drugs in this combination product, can greatly raise the amount of simvastatin in your body.
This can lead to serious side effects, including liver damage, kidney failure, and muscle pain and weakness.
Heart drugs
Using certain heart drugs with amlodipine/valsartan raises your risk of very low blood pressure and increased potassium levels.
It can also harm your kidneys. Examples of these drugs include:
angiotensin receptor blockers (ARBs), such as:
losartan
olmesartan
telmisartan
angiotensin-converting enzyme (ACE) inhibitors, such as:
enalapril
lisinopril
captopril
AMLODIPINE-VALSARTAN MAY INTERACT WITH OTHER MEDICATIONS
Pain drugs
In people who are older or have kidney problems, the use of this medication along with NSAIDs (nonsteroidal anti-inflammatory drugs) can cause serious kidney damage.
Examples of NSAIDs include:
ibuprofen
naproxen
Diuretics (water pills)
Amlodipine/valsartan can cause low blood pressure.
Your risk of low blood pressure is increased if you also take diuretics.
Symptoms of low blood pressure can include dizziness or feeling faint, or chest pain.
Examples of diuretics include:
hydrochlorothiazide
furosemide
HOW TO TAKE AMLODIPINE-VALSARTAN
All possible dosages and drug forms may not be included here.
Your dosage, drug form, and how often you take the drug will depend on:
your age
the condition being treated
how severe your condition is
other medical conditions you have
how you react to the first dose
DOSAGE FOR HYPERTENSION
Generic: Amlodipine/valsartan
Form: oral tablet
Strengths:
5 mg amlodipine/160 mg valsartan
10 mg amlodipine/160 mg valsartan
5 mg amlodipine/320 mg valsartan
10 mg amlodipine/320 mg valsartan
Adult dosage (ages 18 years and older)
Your doctor may start you on a dosage of 5 mg amlodipine/160 mg valsartan once daily.
If your blood pressure is not controlled after 1–2 weeks, your doctor may increase your dosage.
The maximum dosage is 10 mg amlodipine/320 mg valsartan once daily.
Manufacture By: interMed
Marketed By: Khan Sehat LTD
