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What to know about antibiotics

Antibiotics, also known as antibacterial, are medications that destroy or slow down the growth of bacteria.

They include a range of powerful drugs and are used to treat diseases caused by bacteria.

Antibiotics cannot treat viral infections, such as cold, flu, and most coughs.

This article will explain what antibiotics are, how they work, any potential side effects, and antibiotic resistance.

Fast facts on antibiotics

·     Alexander Fleming discovered penicillin, the first natural antibiotic, in 1928.

·     Antibiotics cannot fight viral infections.

·     Fleming predicted the rise of antibiotic resistance.

·     Antibiotics either kill or slow the growth of bacteria.

·     Side effects can include diarrhea, an upset stomach, and nausea.

What are antibiotics?

Antibiotics are powerful medicines that fight certain infections and can save lives when used properly. They either stop bacteria from reproducing or destroy them.

Before bacteria can multiply and cause symptoms, the immune system can typically kill them. White blood cells (WBCs) attack harmful bacteria and, even if symptoms do occur, the immune system can usually cope and fight off the infection.

There are occasions, however, when the number of harmful bacteria is excessive, and the immune system cannot fight them all. Antibiotics are useful in this scenario.

The first antibiotic was penicillin. Penicillin-based antibiotics, such as ampicillin, amoxicillin, and penicillin G, are still available to treat a variety of infections and have been around for a long time.

There are several types of modern antibiotics, and they are usually only available with a prescription in most countries. Topical antibiotics are available in over-the-counter creams and ointments (OTC).

Resistance

There is concern that antibiotics are being overused, and that this overuse contributes toward the growing number of bacterial infections that are becoming resistant to antibacterial medications.

According to the Centers for Disease Control (CDC), outpatient antibiotic overuse is a problem. Antibiotic use appears to be higher in some regions, such as the Southeast.

Use of carbapenems, a major class of last-line antibiotics, increased significantly from 2007 to 2010.

How do antibiotics work?

There are different types of antibiotic, which work in one of two ways:

·         A bactericidal antibiotic, such as penicillin, kills the bacteria. These drugs usually interfere with either the formation of the bacterial cell wall or its cell contents.

·         A bacteriostatic stops bacterium from multiplying.

Side effects

Antibiotics commonly cause the following side effects:

·         diarrhea

·         nausea

·         vomiting

·         rash

·         upset stomach

·         with certain antibiotics or prolonged use, fungal infections of the mouth, digestive tract, and vagina

Less common side effects of antibiotics include:

·         formation of kidney stones, when taking sulphonamides

·         abnormal blood clotting, when taking some cephalosporins)

·         sensitivity to sunlight, when taking tetracyclines

·         blood disorders, when taking trimethoprim

·         deafness, when taking erythromycin and the aminoglycosides

How to use

fvgPeople usually take antibiotics by mouth. However, doctors can administer them by injection or apply them directly to the part of the body with infection.

Most antibiotics start combating an infection within a few hours. It is important to complete the whole course of medication to prevent the return of the infection.

Stopping the medication before the course has finished means that there is a higher chance the bacteria will become resistant to future treatments. This is because the ones that survive have had some exposure to the antibiotic and may consequently develop resistance to it.

An individual need to complete the course of antibiotic treatment even after they see an improvement in symptoms.

Do not take some antibiotics with certain foods and drinks. Take others on an empty stomach, about an hour before meals, or 2 hours after. Follow the instructions correctly for the medication to be effective. People taking metronidazole should not drink alcohol.

Avoid dairy products when taking tetracycline, as these might disrupt the absorption of the medication.